Simultaneous Measurement of Three Tocopherols, All-trans-retinol, and Eight Carotenoids in Human Plasma by Isocratic Liquid Chromatography
نویسندگان
چکیده
منابع مشابه
Simultaneous determination of retinol, carotenoids and tocopherols in human serum by high pressure liquid chromatography.
The determination of serum vitamins having antioxidant properties has gained in importance in recent years. This is mainly due to the observation that an inverse correlation exists between blood levels of these vitamins, including retinol, carotenoids and tocopherol, and diet-related chronic diseases such as coronary heart disease and cancers. This laboratory has been carrying out a series of s...
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A simple and sensitive isocratic reversed-phase high-performance liquid chromatography (HPLC) method for simultaneous determination of retinol, alpha-tocopherol and six carotenoids in human plasma was described. Sample preparation of the earlier published method was further developed by addition of ultrapure water, which enabled aqueous layer to freeze facilitating phase separation without pipe...
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BACKGROUND Epidemiologic evidence suggests that the concentrations of antioxidant vitamins in human plasma may play an important role in numerous chronic diseases, such as cancer and cardiovascular disease. However, methods for simultaneous measurement of these antioxidants are scarce. We developed and validated a new HPLC method for simultaneous determination of these vitamers in human plasma ...
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The roles of carotenoids, retinol, and tocopherols in breast cancer etiology have been inconclusive. The authors prospectively assessed the relations between plasma alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein/zeaxanthin, retinol, alpha-tocopherol, and gamma-tocopherol and breast cancer risk by conducting a nested case-control study using plasma collected from women enrol...
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ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2011
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chrsci/49.3.221